Upstream Bio, Inc. (UPB): Valuation

TTM figures as of June 30, 2026

Upstream Bio, Inc. trades at a -43.48% free-cash-flow yield. That FCF yield is higher than 9% of its own month-end history back to 2024.

Earnings yield -49.87%.

23 month-end valuation observations are on file, starting October 2024.

Sector comparison uses 2682 Healthcare names.

Frequently asked questions

Is UPB cheap versus its own history?

Upstream Bio, Inc. trades at a -43.48% free-cash-flow yield. That FCF yield is higher than 9% of its own month-end history back to 2024.

What is UPB's free-cash-flow yield?

Upstream Bio, Inc. currently yields -43.48% of market cap as trailing free cash flow.

Where do these valuation figures come from?

Yields and quality metrics are computed from the same SEC TTM figures as the financials page, against the live market cap. Historical bands reconstruct month-end market cap from split-adjusted closes and the share count in the units it was filed, then divide by those dollar totals. Nothing here is a third-party estimate.

Source: SEC filings for the fundamentals; split-adjusted Yahoo closes and recorded stock splits for historical market cap.

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