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Spyre Therapeutics, Inc. (SYRE): Short Interest History

The most recent FINRA short interest report for SYRE (settlement date August 14, 2026) shows 11,755,434 shares sold short , a change of -3.20% from the prior report .

Days to cover: 15.95.

FINRA settlement history

Settlement date Short interest Change Avg daily volume Days to cover
Aug 14, 2026 11,755,434 -3.20% 736,817 15.95
Jul 31, 2026 12,143,879 -2.92% 898,547 13.52
Jul 15, 2026 12,508,710 -8.30% 1,385,250 9.03
Jun 30, 2026 13,640,183 8.11% 2,455,257 5.56
Jun 15, 2026 12,616,535 -0.09% 1,165,484 10.83
May 29, 2026 12,627,576 1.70% 816,178 15.47
May 15, 2026 12,417,051 1.60% 1,189,799 10.44
Apr 30, 2026 12,221,682 4.70% 1,217,137 10.04
Apr 15, 2026 11,672,747 11.85% 1,587,932 7.35
Mar 31, 2026 10,435,737 4.39% 909,125 11.48
Mar 13, 2026 9,997,086 0.12% 714,840 13.99
Feb 27, 2026 9,985,198 1.24% 803,682 12.42
Feb 13, 2026 9,862,924 -1.18% 663,160 14.87
Jan 30, 2026 9,980,496 -0.89% 491,985 20.29
Jan 15, 2026 10,069,741 -13.47% 724,793 13.89
Dec 31, 2025 11,636,998 -1.53% 827,619 14.06
Dec 15, 2025 11,818,159 5.92% 852,169 13.87
Nov 28, 2025 11,157,711 -10.49% 610,966 18.26
Nov 14, 2025 12,464,842 0.46% 618,472 20.15
Oct 31, 2025 12,407,305 -7.34% 1,043,667 11.89
Oct 15, 2025 13,390,470 -7.39% 1,456,858 9.19
Sep 30, 2025 14,459,688 4.93% 795,084 18.19
Sep 15, 2025 13,780,763 -2.17% 483,003 28.53
Aug 29, 2025 14,087,087 6.82% 479,985 29.35

Frequently asked questions

What is short interest in SYRE?

Short interest is the total number of SYRE shares currently sold short but not yet covered or closed out. FINRA publishes this data twice monthly.

How is SYRE short interest calculated?

Short interest is aggregated from member firm reports to FINRA. Every U.S. broker-dealer must report aggregate short positions in each security as of the 15th and last trading day of each month.

What does a high short interest mean?

Higher short interest can indicate bearish sentiment, but it also raises the potential for a short squeeze if positive news forces short sellers to cover their positions simultaneously. Compare short interest to float (short percent of float) for context.

Source: FINRA short interest reports, published bi-monthly.

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